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Molecular basis promoting centriole triplet microtubule assembly
Nature
The triplet microtubule, a core structure of centrioles crucial for the organization of centrosomes, cilia, and flagella,...
miesiąc temu
Scientists reconstruct assembly of the human centriole, image by image, for the first time
Phys.org
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles.
2 tygodnie temu
Time-series reconstruction of the molecular architecture of human centriole assembly
ScienceDirect.com
Centriole biogenesis, as in most organelle assemblies, involves the sequential recruitment of sub-structural elements that will support its...
2 tygodnie temu
The evolution of centriole degradation in mouse sperm
Nature
We propose that the evolutionary transition of centrioles with a canonical structure in basal vertebrates and Tetrapods, to an atypical...
3 miesiące temu
New framework for 4D visualization of cell organelles
Wiley Analytical Science
I consent to Wiley's Terms of Use and processing of my personal data as disclosed in Wiley Privacy Policy. I consent to special offers,...
tydzień temu
Localization of Plk4 foci and procentrioles in relation to the mother...
ResearchGate
Download scientific diagram | Localization of Plk4 foci and procentrioles in relation to the mother centriole microtubule wall. (A) Images of Plk4 foci...
6 miesięcy temu
Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ...
Nature
A tight synchrony between the DNA and centrosome cycle is essential for genomic integrity. Centriole disengagement, which licenses...
6 miesięcy temu
Dual roles of CCDC102A in governing centrosome duplication and cohesion
ScienceDirect.com
In animal cells, the dysregulation of centrosome duplication and cohesion maintenance leads to abnormal spindle assembly and chromosomal instability,...
2 miesiące temu
Prolonged overexpression of PLK4 leads to formation of centriole rosette clusters that are connected via canonical ...
Nature
Centrosome amplification is a hallmark of cancer and PLK4 is one of the responsible factors for cancer associated centrosome amplification.
2 miesiące temu
Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells ...
Nature
Using multidisciplinary approaches, we showed that two long coiled-coil proteins, Cep63 and Cep152, form a heterotetrameric building block that...
9 miesięcy temu