Your body has enzymes, such as the cytochrome p450 (CYP) and others, that process many types of medications. This is called metabolism. It also has a way to get rid of drugs, usually though your ...

Similar to grapefruit, medications known as cytochrome P450 (CP450) inhibitors and substrates can delay how long it takes sildenafil to work and can increase your chance of side effects.

Physicians have adopted a one-size-fits-all approach to direct oral anticoagulants that must be reconsidered, says Geoffrey ...

Various isoforms of the enzyme cytochrome P450 are responsible for the oxidative metabolism of many drugs 15. One of the isoforms of P450, CYP3A4, is found in the gut wall, and it metabolizes ...

This article examines the opinion of three experts on the safety of consuming grapefruit before bed. The experts agree that ...

Department of Bioscience and Technology, Institute of Graduate Studies and Research, Alexandria University, 163 Horreya Ave., PO Box 832, Alexandria, Egypt ...

We identified a cytochrome P450 hydroxylase gene specific to the trichome gland and used both antisense and sense co-suppression strategies to investigate its function. P450-suppressed transgenic ...

Scientists from Gwangju Institute of Science and Technology in Korea unveil compound 11c, a groundbreaking oral treatment for ...

Since 2005, the Committee on Engaged Learning has awarded more than $5 million—$5,172,335.57 to be exact—in competitive Odyssey grants to support 1,561 projects by Hendrix students, faculty, and staff ...

New Delhi: Advising to conduct the Phase IV clinical trial, the Subject Expert Committee (SEC) functional under the Central ...

Ahn. Beyond its therapeutic potential, compound 11c displays an excellent safety profile, exhibiting hepatocyte and plasma stability, minimal cytotoxicity, and low cytochrome P450 inhibition.