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cyklooksygenaza z books.google.com
The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases (COXs) are enzymes responsible for the formation of an important class of biological mediators called ...
cyklooksygenaza z books.google.com
In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors.
cyklooksygenaza z books.google.com
One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.
cyklooksygenaza z books.google.com
This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.
cyklooksygenaza z books.google.com
This is followed by a section on the epidemiology of NSAIDs and cancers of the colon and breast, and other anatomic sites.
cyklooksygenaza z books.google.com
Since then, there has been intense interest in the interaction between this diverse group of inhibitors and the enzyme known as cyclooxygenase (COX). It exists in two isoforms, COX-l and COX-2 (discovered some 5 years ago).
cyklooksygenaza z books.google.com
Besides, the book contains a series of chapters examining the link between COX-2 and cancer in specific organs (e.g. skin, breast, cervix, digestive tract, lung, etc.).
cyklooksygenaza z books.google.com
The mainstay of therapy for rheumatoid disease is the non-steroid antiinflammatory drugs (NSAIDs), despite their inherent gastrointestinal toxicity and ability to cause renal damage in susceptible patients.
cyklooksygenaza z books.google.com
Timely and authoritative, the methods in this book will help their users in exploring the pathobiology of inflammation.