CYFRA 21-1 (Cytokeratin 19 Fragment) in Lung Cancer
- 1. CYFRA 21-1 has been demonstrated as clinically useful in prognostication and monitoring.
- 2. Elevated pretreatment CYFRA 21-1 in NSCLC is reported to be associated with unfavorable prognosi… See more
Clinical sensitivity: varies by disease stage6Patel JL, Erickson A, Roberts WL, et al. Performance characteristics of an automated assay for the quantitation of CYFRA 21-1 in human serum. Clin Biochem. 2010;43(18):1449-1452. Analytic sensitivity: limit of … See more
Lung cancer is the second most common cancer in the U.S. and the most common cause of cancer-related deaths in both men and women. See more
- 1. Cytokeratins are intermediate filament structural proteins found in the cytoskele…
- 2. The two types of cytokeratins are:
- 3. Release of cytokeratins into the circulation occurs by numerous mechani…
- 4. Cytokeratins … See more
- 1. Test is not suitable for lung cancer screening
- 2. Results obtained with different tests or kits cannot be used interchangeably.
- 3. Test interference may occur with:
- 4. CYFRA … See more
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Differential diagnostic CYFRA 21-1 level for benign and malignant ...
WEBNov 9, 2012 · The CYFRA 21-1 assay, which detects a soluble fragment of cytokeratin 19 that is expressed by all histological types of lung cancer, is capable of detecting …
- Author: Rong Biaoxue, Yang Shuanying, Cai Xiguang, Zhang Wei, Li Wei
- DOI: 10.5114/aoms.2012.30831
- Publish Year: 2012
- Publication: Arch Med Sci. 2012 Nov 9; 8(5): 756-766.
CYFRA21-1 tests in the diagnosis of non-small cell lung cancer: A …
WEBAug 22, 2019 · Objective: The aim of the study was to evaluate the diagnostic value of soluble fragment of cytokeratin 19 (CYFRA21-1) tests in detecting non-small cell lung …
- Author: Lei Fu, Lei Fu, Rong Wang, Ling Yin, Xiaopu Shang, Runtong Zhang, Pengjun Zhang
- Estimated Reading Time: 9 mins
- Publish Year: 2019
- Studies of cyfra_
Systematic review of CYFRA 21-1 as a prognostic indicator and its ...
WEBJan 1, 2017 · Systematic review of CYFRA 21-1 as a prognostic indicator and its predictive correlation with clinicopathological features in Non-small Cell Lung Cancer: A meta …
- Author: Zipu Yu, Guofei Zhang, Maoying Yang, Sai Zhang, Baiqin Zhao, Gang Shen, Ying Chai
- DOI: 10.18632/oncotarget.14022
- Publish Year: 2017
- Publication: Oncotarget. 2017 Jan 17; 8(3): 4043-4050.
CYFRA 21-1 as a prognostic and predictive marker in advanced …
WEBResults. Lower baseline CYFRA levels were associated with both longer overall survival and failure free survival (p<0.0001 and p=0.0003). In addition, larger reductions in …
- Author: Martin J. Edelman, Lydia Hodgson, Paula Y. Rosenblatt, Robert H. Christenson, Everett E. Vokes, Xiao...
- DOI: 10.1097/JTO.0b013e31824a8db0
- Publish Year: 2012
- Published: 2012/04
CYFRA 21-1 is a prognostic determinant in non-small …
WEBMay 4, 2004 · British Journal of Cancer - CYFRA 21-1 is a prognostic determinant in non-small-cell lung cancer: results of a meta-analysis in 2063 patients
Diagnostic accuracy and prognostic applications of CYFRA 21-1 in …
WEBMay 9, 2019 · CYFRA 21–1 is a cytoplasmic protein fragment of cytokeratin 19 (CK-19) which is found in various epithelial malignancies, such as lung cancer[21, 22], …
Systematic review of CYFRA 21-1 as a prognostic indicator and its ...
WEBJan 17, 2017 · Aim: To evaluate the value of Cytokeratin 19 fragment for its survival prognostic indicator and predictive correlation with clinicopathological features in Non …
Cyfra 21-1 as a Biologic Marker of Non-small Cell Lung Cancer ...
WEBJul 1, 1995 · We conclude that Cyfra 21-1, a soluble fragment of cytokeratin 19, is more sensitive and specific than other markers in NSCLC. Its level correlates with disease …
CYFRA 21-1 in patients with suspected cancer: evaluation of an …
WEBThis new cutoff decreases the false positive rate and improves the diagnostic efficacy of CYFRA 21-1 as a tumor marker as well as its association with death events. Keywords: …
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