This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology.

In the first chapter, we provide context for the work by discussing three distinct biological consequences of AHR activation.

The aryl hydrocarbon receptor (AHR) and estrogen receptors (ERs) are ligand-activated transcription factors and members of the basic helix-loop-helix PER-ARNT-SIM (bHLH-PAS) and nuclear receptor (NR) superfamilies, respectively.

... (AhR) contributes to immune homeostasis as having an antimicrobial role on the one hand – owing to AhR-dependent IL-22 transcription – and, on the other, an anti ... AhR axis in host–microbial symbiosis The promiscuous nature of AhR agonists.

Taken together, this document outlines novel mouse models that may be used by the toxicology community to better understand AHR biology.

... Ahr forms a division between the upper and lower Rhinecountry , both with respect to the inhabitants and language . Immediately above it at Rheineck the dialect of the upper Rhine begins , whilst the people of the Ahrvalley speak the ...

... Ahr - Eifel . Microbial activity , microbial biomass - C ( Cmic ) , metabolic quotient ( qCO2 ) and the ratio of microbial C to soil organic carbon ( Cmic / Corg ) have all been proposed to be indicators for soil quality in many studies ...

In chapter two we share characterization data of candidate genetic modifiers of AHR signaling as identified in the literature and define the phenotypes of interest we use to characterize the AHR null and potential phenocopy models.