This work focuses on the understanding of IL-12, including its production, receptor interactions, signal transduction, interactions with other cytokines, its use as a therapy for AIDS and cancer, and its role in promoting an effective ...
This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy.
The contributions collected in this volume represent the most recent findings, reviewed by leading scientists in the field, on several different aspects of IL-12 biology.
The aim of this study was to investigate the mechanisms exerted by complexed linear DNA vectors encoding Interleukin (IL-) 12 and IL-18 applied in vivo in horses.
In this book, an interdisciplinary approach combining dynamic quantitative measurements with mathematical modelling is used to solve two different problems in molecular immunology.
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment.