“About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of ...
“About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of ...
As a new member of the helper T cell subsets, Th17 cells have triggered more and more interest in exploring their development, regulation, function and therapeutic manipulation in distinct context since they were identified in 2005.
The work presented here describe how we identified the soluble factors required for the differentiation of human TH17 and TH9 cells, which are two novel TH subsets implicated in the pathogenesis of various autoimmune and allergic disorders, ...
Psoriasiform diseases are a group of cutaneous disorders that are characterized by impaired keratinocyte maturation leading to epidermal hyperplasia and thickening of skin.