... UTRs, we constructed control reporters where the 3'UTRs have point-mutations in computationally predicted microRNA binding sites to abolish their repressive effects (see section 4.2). m C h e r ry n o i s e A 102 103 104 0 0.5 1 Lats2 3 ...
... UTRS III UTRS I & VI UTRS III UTRS I & VI UTRS II UTRS I UTRS XIII UTRS VI & VII UTRS VII UTRS I UTRS II UTRS II UTRS VII UTRS I & VI UTRS VII UTRS I & VI UTRS VII UTRS VI UTRS I ... UTRS XII UTRS VIII & IX UTRS XI UTRS X UTRS XI 696 MAPS.
... UTRs correspond to lower expression rates since they often contain more miRNA and protein binding sites that are involved in inhibiting translation. Humantranscripts possess 3'-UTRs that are on average twice as long as other mammalian 3'- ...
... UTRs ( 23,24 ) . Little is yet known about the 5 ' UTRs in brain GHR transcripts other than the fact that the liver - specific rat GHR1 exon ( V2 in the terminology of Domene et al . ) is not detectable in brain ( 25 ) , whereas the 5 ' UTR ...
... UTRs are much larger in humans. The length of C. elegans 5◦UTRs is likely an underestimate due to the prominent trans-splicing of distinct “splice leader” sequences to the 5◦ ends of mRNAs in this organism The common feature of the ...
... UTRs and 14.1% encodes 3'UTRs. The functional significance of these UTR sequences is not fully elucidated. However, features present in four of the 5'UTRs from the EBOV VP35, VP30, VP24 and L mRNAs, are short upstream open reading ...
... UTRs, it did show that binding of both UTRs acted synergistically to enhance repression. Another fascinating point not expounded on was the possibility of miRNAs to bind more than one target mRNA at a time. This research showed that miR ...
... UTRs The mRNA UTRs are non-coding regions located 50 upstream and 30 downstream of ORFs. These enable protein translation and provide stability by interacting with RNA-binding proteins (Mignone et al., 2002). The 50-UTR is essential for ...
... UTRs have a role in subcellular transport and targeting . The 5 ' UTRs are generally looked upon as being primary or secondary sequences that regulate the translational efficiency of the mRNA . The 3 ' UTRs ( and some 5 ' UTRs ) are ...