Integron - Wikipedia
WebIntegron - Wikipedia. Contents. hide. (Top) Discovery. Integron function. Structure. Gene cassettes. Occurrence. Terminology. References. Further reading. External links. Integrons are genetic mechanisms that allow bacteria to adapt and evolve rapidly through the stockpiling and expression of new genes. [1] .
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Integrons: agents of bacterial evolution | Nature Reviews …
WebAug 1, 2006 · Integrons are assembly platforms — DNA elements that acquire open reading frames embedded in exogenous gene cassettes and convert them to functional genes by ensuring their correct expression....
Integrons: Past, Present, and Future - PMC - National Center for ...
WebIntegrons are genetic elements that allow efficient capture and expression of exogenous genes. They are widely known for their role in the dissemination of antibiotic resistance, particularly among Gram-negative bacterial pathogens.
Integron cassettes integrate into bacterial genomes via ... - Nature
WebJan 3, 2024 · Integrons are genetic elements involved in bacterial adaptation which capture, shuffle and express genes encoding adaptive functions embedded in cassettes. These events are governed by the...
Integrons - PMC - National Center for Biotechnology Information
WebSep 1, 2012 · Integrons consists of three elements: the gene that encodes a tyrosine recombinase (integrase, encoded by the intI gene), needed for site-specific recombination within the integron; the adjacent recombination site ( attI) that is recognized by the integrase; and the promoter (P c ), located upstream of the integration site, necessary for …
The evolutionary dynamics of integrons in changing environments
WebFeb 5, 2016 · Integrons are genetic elements that are common in bacteria and are hotspots for genome evolution. They facilitate the acquisition and reassembly of gene cassettes encoding a variety of functions,...
Integron Functionality and Genome Innovation: An Update on the …
WebJan 20, 2022 · Introduction. Integron Functionality Is Directly Linked with Adaptation on Demand. Integrons are versatile genetic platforms involved with the acquisition, stockpiling, excision, and rearrangements of gene cassettes by site-specific recombination events mediated by integrase activity [ 1 ].
Integron - an overview | ScienceDirect Topics
WebAn integron consists of a recognition region, the attI site, into which a variety of gene cassettes may be integrated, plus a gene encoding the enzyme responsible for insertion, the integrase. The attI site is flanked by two 7 bp sequences that act as recognition sites for the integrase ( Fig. 25.28 ).
Integrons: Past, Present, and Future | Microbiology and Molecular ...
WebSUMMARY. Integrons are versatile gene acquisition systems commonly found in bacterial genomes. They are ancient elements that are a hot spot for genomic complexity, generating phenotypic diversity and shaping adaptive responses. In recent times, they have had a major role in the acquisition, expression, and dissemination of antibiotic ...
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